UDCORE-II is Microcore's flagship undenatured collagen product, meticulously derived from young chicken sternum through a unique backward integration process. Our production facility adheres to the highest global standards, ensuring purity and efficacy across all batches.
Strategic Integration
This product is supplied only as a formulated product or finished product. It is not supplied as an independent ingredient, ensuring the integrity of the therapeutic application.
The glycosylated form of Undenatured Collagen II interacting with DCs in GALT.
The key feature of UDCORE-II is its integrated epitope or antigenicity. Undenatured Collagen Type-II has a specific mechanism of action designed to be taken up by Dendritic Cells (DCs) in the Gut-Associated Lymphoid Tissue (GALT) in its glycosylated form.
Synthesis of endogenous collagen or supplementation with collagen peptides becomes effective once the immune response is adequately suppressed.
Step-by-step biological process flow showing how Undenatured Collagen Type II acts on the gut immune tissue to protect joint cartilage.
Undenatured Collagen Type II (Native Glycosylated Form)
Undenatured collagen molecules are taken up by Dendritic Cells (DCs) in the Gut-Associated Lymphoid Tissue (GALT) in their native, glycosylated form without being digested or altered.
This process allows T helper cells to recognize the antigen epitopes, leading to a controlled, mild initial immune response that sensitizes the immune network
Continuous contact contributes to the gradual development of Oral Tolerance, meaning the autoimmune response against cartilage collagen II becomes attenuated and controlled.
Oral tolerance stimulates T regulatory cells and suppresses T helper cells, ultimately leading to the effective suppression of inflammatory cartilage destruction in the joints.
Once the autoimmune attack is successfully suppressed, the synthesis of endogenous collagen and supplementation with active collagen peptides becomes highly effective for tissue repair.
The sternum is a soft cartilage organ found in the central part of the chicken breast bone. Microcore selects only young chickens to ensure flexible sternum cartilage, maximizing the extraction of high-quality Collagen Type II with active, integrated epitopes.
Our Natural Chicken Sternum Collagen Complex contains a balanced profile of bioactive components:
UDCORE-II contains integrated epitopes or antigenicity. In its glycosylated form, it is taken up by Dendritic Cells (DCs) in the GALT. This triggers T helper cells to recognize the antigen epitopes, inducing an initial mild immune response that gradually develops into Oral Tolerance. This attenuates the immune response against cartilage collagen II, stimulating T regulatory cells and suppressing inflammatory cartilage destruction.
It specifically helps Rheumatoid Arthritis patients by gradually developing Oral Tolerance. This attenuates the immune response against cartilage collagen II, suppressing inflammatory destruction and making endogenous collagen synthesis or supplementation significantly more effective.
Drug Interactions: No negative reports when taken as directed.
Nutrient Depletion: No negative reports when taken as directed.
Toxicity & Adverse Reactions: None known when taken as directed. Technical specifications are available on request.
Yes. Microcore's Undenatured Collagen Type II is produced using patent-granted technologies and is certified by FSSAI/CL/DELHI, HALAL, ISO-22000, and GMP standards.
