Welcome To Microcore Research Labs India (P) Ltd

Microcore is Research & Development based Biotech company that focused on the discovery, development and manufacturing of clinically validated specialty nutraceuticals. Microcore's commitment to addressing chronic conditions indicates a potential contribution to improving the quality of life for individuals dealing with such health challenges. It's also notable that the company has evolved from a research-oriented entity to a fully-integrated, innovation-led global enterprise, suggesting a comprehensive approach to product development and manufacturing. Microcore specializes in the development of nutraceuticals targeting a range of chronic conditions, including Arthritis, Osteoarthritis, Osteoporosis, Osteopenia, Inflammatory diseases, Rheumatoid arthritis, wound healing, tissue regeneration, hair and skin care.

 

It is a great honor to be ranked and chosen amongst an overwhelming number of 37134 nominations filed by SMEs from all over the country and we are delighted to share our happiness with you that MICROCORE  is a winner of  INDIA SME TOP 100 award 2022

Unit-1 R&D infrastructure, Process development and Production facilities are located at Erode the Textile and Turmeric City of South India.(15,000 sqf ) & Unit-2  Asia's largest Egg Shell Membrane processing is under expansion at Tiruchirappalli  to Karur  at (20 Acres). 

Microcore's in-house Research and Development efforts have been recognized by the Department of Scientific and Industrial Research (DSIR) of the Government of India. A cumulative experience of 25 years in research, operation, and manufacturing is indeed a significant accomplishment and a testament to Microcore's commitment to innovation and scientific advancements.

The fact that Microcore is the only company holding PA-II approval for Egg Membrane-based product ranges is a notable achievement. This approval likely signifies that Microcore's products have undergone rigorous testing and evaluation, meeting the necessary standards set by regulatory authorities.
No.01/std/PA/FSSAI/2021
No.02/std/PA/FSSAI/2021
No.02/std/PA/FSSAI/2021 (Part 1)
No.60/std/PA/FSSAI/2022

1.Health Claim  :-  Microcore Natural Egg Shell Membrane promoting the healthy maintenance of joints and connective tissues.

2.Health Claim :-  Microcore Natural Egg shell Calcium preventing the risk of Osteoporosis.

 

The approval and sanctioning of the Nutraceutical Egg membrane formulation through Form II application! This achievement, combined with Trade Mark registration, granted patents for both the process and the product and exclusive Clinical Trials Registry-India (CTRI) registered clinical studies, reflects a comprehensive and well-documented approach to the development of your nutraceutical product. Moreover, the fact that these Nutraceutical are produced in a facility certified under Good Manufacturing Practices (GMP), ISO-22000, Halal certified. Adhering to these quality standards ensures the safety, efficacy, and quality of the products, which is crucial in the nutraceutical industry. Microcore current focus is on selling branded bio-actives as ingredients, blends, and finished products under brand name MUTTAIJOW COMPLEX® , MUTTAIODUJOW® , UDCORE-ii®, AKBACORE® & CUMINCORE® with  strategic approach to branding and product differentiation. Microcore has conducted comparative clinical studies of Egg Shell Membrane-based nutraceutical combinations versus Diacerin-based drug combinations in knee osteoarthritis patients is commendable. Such scientific validation and research contribute to the credibility of the products and can play a crucial role in gaining trust among consumers and healthcare professionals.

 

Significances of Clinical Studies by Microcore

 

Clinical studies CTRI/2021/08/035335 & CTRI /2023/02/049901 conducted by  MICROCORE  consolidated  Egg Membrane and Egg Calcium formula for many health benefits. 

 

Microcore is the first company that has successfuly completed clinical studies to prove that Natural Egg Shell Membrane based Nutraceuticals combinations are equivalent or better than Diacerin based drug Combinations, for more details pl refer | http://jointcore.us/

 

* Reference :- A randomized, open‑label, multicentered parallel‑group clinical study to evaluate the efficacy and safety of Joint Core® compared to Jointace DN  in osteoarthritis patients  2022 Journal of Current Research in Scientific Medicine | Published by Wolters Kluwer  Medknow jcrsm_21_22_R2_OA 10.4103/jcrsm.jcrsm_21_22  JOURNAL- DOWNLOAD

 

* Reference :-  A RANDOMIZED, OPEN LABEL, MULTICENTER PARALLEL GROUP CLINICAL STUDY COMPARING THE RELATIVE BIOAVAILABILITY, SAFETY AND EFFICACY OF MICROCORE NESCŪ WITH CALCIUM CARBONATE AND CALCIUM CITRATE MALATE IN OSTEOPENIC AND OSTEOPOROTIC PATIENTS Indian Journal of Orthopaedics Received: 29 November 2023 / Accepted: 30 January 2024 Indian Orthopaedics Association 2024 www.eggcalcium.com | https://link.springer.com/article/10.1007/s43465-024-01117-3

 

Results

  • Joint Core®  www.jointcore.us its potential benefits for managing Osteoarthritis.
     1.Creatinine Reduction :-  Claimed to reduce Sr Creatinine values by 25% from 1.1 (+/-) 1.0 at zero day to 0.83 (+/-) 0.19 in 12 weeks.

  • 2.Anti-inflammatory Activity:- Claimed that it has anti-inflammatory activity, as evidenced by the control of HS-CRP inflammatory markers from 7.15 (+/-) 4.6 to 3.86 (+/-) 2.91 and ESR inflammatory markers from 45.75 (+/-) 32.83 to 9.0 (+/-) 4.5 in 12 weeks.

  • 3.Fibrinogen Levels:-  Claimed to reduce inflammatory markers, specifically Fibrinogen Levels, from 309.29 (+/-) 96.31 to 9.0 (+/-) 4.5 in 12 weeks.

  • 4.Improvement in Osteoarthritis Patients: Show significant improvement in Osteoarthritis patients, addressing pain, reducing inflammatory markers, and improving functional capacity.

  • 5.Natural Supplement:-  The product is described as a natural supplement containing Natural eggshell membrane (MuttaiJowComplex®), ABKACORE® (Boswellia serrata) & CUMINCORE® (Curcumin extract96%).

  • 6.Pain Management: It is claimed to provide better and early pain management, as per comparative data on PAIN VAS SCALE, WOMAC PAIN SUB SCALE, GLOBAL ASSESSMENT ON IMPROVEMENTS ON OSTEOARTHRITIS SCORE, OMERACT-OARSI.

  • 7.Equivalent to Reference Drug:- It is suggested to be equivalent to the reference drug combination Jointace DN in managing Osteoarthritis, reducing inflammation, providing pain relief, and improving functional capacity, without major side effects or drug interactions.

  • 8.NF-kB Activation:-The product claims to activate the level of nuclear factor kappa-light-chain-enhancer of activated B cells ("NF-kB") in the gut, helping in NF-kB dys-regulations.

  • 9.Reduction of Pro-inflammatory Cytokines: It is claimed to reduce early-phase pro-inflammatory cytokines like IL-6, IL-10, and TNF-α,β involved in later phases of the inflammatory process.

Benefits of Microcore's UD-Core-II®

UDCORE-ii, which is Microcore's Undenatured Chicken Sternum Collagen Complex II. This product is derived from chicken sternum through a backward integration process and is produced using various certifications such as ISO-22000, GMP, FSSAI/CL, HALAL, and Kosher. The key feature of UDCORE-ii ®is its integrated epitope or antigencity. Undenatured Collagen Type-II has a specific mechanism of action. It is designed to be taken up by Dendritic cells (DCs) in the Gut-Associated Lymphoid Tissue (GALT) in its glycosylated form. This process allows T helper cells to recognize the antigen epitopes, leading to an initial mild immune response. Over time, this can contribute to the development of oral tolerance, which means the immune response against cartilage collagen II is attenuated. The gradual development of oral tolerance is crucial in suppressing the immune response against collagen II. This stimulation of T regulatory cells and suppression of T helper cell response can ultimately lead to the effective suppression of inflammatory cartilage collagen destruction. As a result, the synthesis of endogenous collagen or supplementation with collagen peptides becomes more effective once the immune response is adequately suppressed.The use of patent-granted technologies in the production of UDCORE-ii adds to its uniqueness and potentially enhances its effectiveness in promoting oral tolerance and addressing issues related to cartilage collagen destruction. It's worth noting that this information is specific to the details you provided and may be subject to further scientific research and development..

 

 

Branded Bioactives of Microcore

Microcore has two ranges of branded Natural Egg Shell membrane that includes Muttaijow Complex® ,Muttaiodujow®  and UDCORE -ii ® which are clinically studied.

Research

R & D is a fundamental part of Microcore's core strategy. We use our knowledge in biotechnology .

Intellectual properties

Registered nine patents with Idian Patent Organization.

 products

Biofilm of Natural Egg Shell Membrane, Collagen- II Concentrate.
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Why to work with Microcore?

"First Time an international product is available in India"

Microcore manufactures  high pure Natural Egg Membrane Collagen ranges of products, Undenatured Collagen Type-II and Microcore NESC through patented technologies in FSSAI, GMP,ISO-22000, Kosher and Halal approved facilities.

 

 http://www.jointcore.us   http://www.eggcalcium.com

 

 

 

 

 

 

 

 

 

 

Gallery

We constantly work on developing highly innovative nutraceutical molecules
 

 

 

 

akbanem®

Top sellling brands
AKBANEM® Contains Natural Egg Membrane 96 % MUTTAIJOW COMPLEX® 500 mg + AKBACORE® 300 mg

 

 

JOINTCORE®

Top selling brands
JOINTCORE® Contains Natural Egg Membrane 96 % MUTTAIJOW COMPLEX®400 mg + AKBACORE® 90mg + CUMINCORE ®10mg
 

synovcore®

Top selling brands
SYNOVCORE® Contains Natural Egg Membrane 96 % MUTTAIJOW COMPLEX® 500 mg + AKBACORE® 90mg + CUMINCORE ®10mg
 

EPITOPCORE ®

Top selling brands
EPITOPCORE® contains 500 mg of Natural Egg Shell Membrane MUTTAIODUJOW®  +UDCOREii ® (Undenatured Collagen Type- ii 40 mg)+ AKBACORE ® 50 mg+
 

TRICHOVITALS®

Top selling brands
TRICHOVITALS®   contains  Natural Egg Membrane MUTTAIJOW COMPLEX ® 450mg + ELLAGIC ACID (90%) (an extract from Pomogranet fruit) 5mg + Sabbery (10%) b glucogallin (an extract from Amla fruit)5 mg,+ Biotin ( a water soluble vitamin) 25 mcg+ Curcuminoids 5mg + Murraya koenigii ( Curry leaf) 30 mg

 

 

Our Latest Blog

Latest News

January 2024

Akums Drugs & Pharmaceuticals Ltd and Microcore has entered into a joint venture to develope Bone and Joint formula for pets

https://www.akums.in/

October 2022

Akums Drugs ties up with Microcore Research to manufacture NESM supplements

https://economictimes.indiatimes.com/small-biz/sme-sector/akums-drugs-ties-up-with-microcore-research-to-manufacture-nesm-supplements/articleshow/95197995.cms

https://nuffoodsspectrum.in/2022/11/01/akums-drugs-ties-up-with-microcore-research-to-develop-supplements-for-healthy-joints.html

https://www.expresspharma.in/akums-drugs-ties-up-with-microcore-research-to-manufacture-nesm-supplements-for-healthy-joints/

http://bwhealthcareworld.businessworld.in/article/Akums-Drugs-Partners-With-Microcore-Research-To-Manufacture-NESM-Supplements-/31-10-2022-452321/

https://www.indiapharmaoutlook.com/news/akums-microcore-research-enter-jv-to-develop-nesm-dietary-supplements-nwid-691.html

 

Exclusive Business partner- India

Posted 12 January 2023

Akums Drugs  Pharma

Maxcure Nutravedics - India

Business partnership  business partnership with Maxcure Nutravedics Ltd and Akums Drugs & Pharmaceuticals to exclusively supply and commercialize products containing Natural Egg Shell Membrane MUTTAIODUJOW® and MUTTAIJOW COMPLEX®. This can be a strategic move, leveraging the manufacturing capabilities of Akums, a prominent CRMO (Contract Research and Manufacturing Organization) in India. Akums is a largest CRMO in India, responsible for manufacturing 20% of all drugs and dietary supplements business in India. It has seventeen dedicated & state of the art manufacturing facilities.

Frequently ask Questions

Ask Questions

  • Why  Microcore's  Natural Egg Shell Membrane ? (Muttaijow Complex®  & Muttaiodu Jow ®)


    it is Natural way of improving your health by adding novel dietary supplement. It contains naturally occurring Collagen Type-I, III, V &,X Elastin, Chondroitin Sulfate , Glycosaminoglycans, Membranous protein, Hyaluronic acid etc and other fractional molecules that includes, Growth factor β, Ovocalixin, Ovocleidin, Ovotransferrin, Desmosine, Isodesmosine and Sulphur-bearing amino acids as essential to maintaining healthy joint and connective tissues,
     

  • Does  Microcore's Natural Egg Shell Membrane have functional Claim and Clinical Studies?  

    Yes the Microcore Natural Egg Shell Membrane are Clinically Validated pl refer  http://www.jointcore.us www.eggcalcium.com for more details?. Both bulk ingredient and the formulated or finished products are available for commercial.

    holds PA-II APPROVAL for Egg Membrane based product ranges that includes

    No.01/std/PA/FSSAI/2021
    No.02/std/PA/FSSAI/2021
    No.02/std/PA/FSSAI/2021 (Part 1)
    No.60/std/PA/FSSAI/2022

    Health Claim :-"Natural Egg Shell Membrane is for Healthy Maintenance of Joints and Connective Tissues"

    Health Claim :-"Microcore NESC to prevent the risk of Osteoporosis"


     

  • What are the specialty of Microcore's UDCore-ii?

    Microcore's UDCore-ii, an undenatured Collagen Type II product made from chicken sternum through backward integration. Here's a breakdown of the key points:
    Source and Production: UDCore-ii is derived from chicken sternum.
    It undergoes a production process that adheres to ISO-22000, GMP (Good Manufacturing Practice), FSSAI/CL (Food Safety and Standards Authority of India/Central License), HALAL certifications, and Patent Granted Technologies.
    Specialty: UDCore-ii contains an integrated epitope or antigenicity.
    Undenatured Collagen II is designed to be taken up by Dendritic cells (DCs) in the GALT (Gut-Associated Lymphoid Tissue) in its glycosylated form.
    Immune Response and Oral Tolerance:
    This uptake induces an initial mild immune response. Over time, it leads to the development of oral tolerance. Oral tolerance is characterized by the immune system becoming tolerant to the antigen, in this case, collagen Type II.
    Impact on T Cells: T helper cells recognize the antigen epitopes, contributing to the immune response.
    The immune response is gradually attenuated, suppressing the destructive immune response against cartilage collagen II.
    Stimulation of Regulatory Cells:
    UDCore-ii stimulates T regulatory cells.
    T regulatory cells play a role in suppressing T helper cell stimulation and response. Effects on Collagen Synthesis: The attenuation of the immune response allows for more effective endogenous collagen synthesis.
    Collagen peptide supplementation can be more effective once the inflammatory destruction of cartilage collagen is suppressed.
    Supply Form: UD-Core-ii is not supplied as an independent ingredient. It is provided only as a formulated or finished product.
    This information suggests that Microcore's Undenatured Collagen II has potential applications in modulating the immune response and promoting oral tolerance, which could be beneficial in conditions related to cartilage collagen. It's important to note that the specifics of any medical or health-related use should be discussed with healthcare professionals.

     

  • What are the pipeline  products of Microcore?
     

     Some of our pipeline product includes | Wound healing Collagen Complex | Hydroxy Apatite for dental procedures and bone surgery| High PDAACS protein from  Fried Bengal Gram | Vitamin K27 from fermented Fried Bengal Gram  | Medium-chain triglycerides (MCTs) from fermented Coconut oil Fermented Turmeric | Soluble Dietary Fiber from BG Husk | Anthocyanian from Red Cabbage |

  • How to differentiate Microcore's products from Unethical products ?

     

    Microcore would supply the products with clinical Study report and complete regulatory documents directly and we don't have any distributors in  any parts of India, hence please do not relay on low cost suppliers and that would disintegrate the efficacy of your finished products. Microcore's position in the market.
    Intellectual Property Protection: Microcore is the sole company in India holding a patent for the Natural Egg Shell Membrane and Chicken Sternum Collagen Type-II product ranges.
    The company also emphasizes complete regulatory compliance.
    Trademark and Branding: Microcore has registered trademarks for its product ranges.
    Clinical Validation: Microcore promotes branded bioactives that have undergone clinical studies and validation. This implies that their products have been scientifically tested to demonstrate efficacy.
    Distribution Model: Microcore does not have any distributors or agencies for its products.The company seems to have a direct-to-consumer or controlled distribution model.
    Warning About Fake Products: Microcore issues a warning about the presence of fake products being sold at low cost. These fake products are claimed to lack medical advantages.
    Microcore explicitly states that it would not be responsible for any fake products purchased from other companies. Consumers are advised to be cautious and ensure they are purchasing authentic products directly from Microcore to benefit from the claimed medical advantages. The emphasis on patents, trademarks, and clinical validation suggests a commitment to quality and authenticity by Microcore.
     


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